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Canadian Journal of Anesthesia, Vol 10, 428-441, Copyright © 1963 by Canadian Anesthesiologists' Society

Blood Carbonic Anhydrase Activity–A Possible Role in the Production of Acid-Base Imbalance in Children and Infants

A. R. BOUTROS F.F.A.R.C.S.1 and V. R. WOODFORD PH.D.2

1 Department of Anaesthesia, University of Saskatchewan, and the University Hospital, Saskatoon, Saskatchewan. Present address: Department of Anesthesia, State University of Iowa, Iowa City, Iowa, U.S.A.
2 Department of Biochemistry, University of Saskatchewan; Saskatoon, Saskatchewan

1. Blood carbonic anhydrase activity was estimated in individuals belonging to four age groups. Our results show that the level of activity in adults is significantly higher than in the newborn.

2. A theory was proposed as to the clinical significance of very low carbonic anhydrase levels in premature babies, the newborn, and very young infants.

Note:

This work was supported by grants from the Medical Research Council (No. MA-1135), and the Dean's Fund, College of Medicine, University of Saskatchewan.






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