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Canadian Journal of Anesthesia, Vol 10, 516-517, Copyright © 1963 by Canadian Anesthesiologists' Society

The Use of Hypotensive Drugs during Electrical Anaesthesia in Dogs

D. F. CAMERON M.D.1 and J.W. R. McINTYRE F.F.A.R.C.S.1

1 Departments of Pharmacology and Anaesthesia, University of Alberta, Edmonton, Alberta

A sine wave alternating current of 50–100 ma., 700 cycles per second, and approximately 15 volts, applied to a dog with fronto-occipital electrodes, produces anaesthesia. Hypertension is an undesirable side-effect. Phenoxybenzamine 5 mg./kg. given intravenously was superior to reserpine 0.1 mg./kg. given intraperitoneally 24 hours previously, trimethaphan 0.01 per cent by intravenous drip, or the same drug in smaller dosage, in preventing this hypertensive response.






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Copyright © 1963 by the Canadian Anesthesiologists' Society.