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Canadian Journal of Anesthesia, Vol 11, 173-181, Copyright © 1964 by Canadian Anesthesiologists' Society
1 Section of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota
The integrity of the circulation depends on the summation of the effects of the cardiac output, the peripheral vascular resistance, and the blood volume Agents producing general anaesthesia affect the circulation by decreasing cairdiac output and peripheral resistance, this effect is in proportion to the concentration of agents in the blood Other factors which mey alter the circulation 14 anaesthesia are the status of ventilation, the degree of hypoxia, the administratlion of relaxants, and the occurrence of metabolic acidosis Along with the lisual clinical means of evaluating the circulation, venoiis piessure values are helpful data These values permit differentiation between a problem in which myocardial functaon needs improvement and one in which blood volume can be safely increased to treat an inadequate circulation
Note:
Read at the meeting of the Ontario Division of the Canadian Anaesthetists' Society, London, Ontario, October 11 and 12, 1963
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