CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MATTHEWS, J. H
Right arrow Articles by HALBERG, F.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MATTHEWS, J. H
Right arrow Articles by HALBERG, F.

Canadian Journal of Anesthesia, Vol 11, 280-290, Copyright © 1964 by Canadian Anesthesiologists' Society

A Circadian Susceptibility-Resistance Cycle to Fluothane in Male B1Mice

JAMES H MATTHEWS MD1, EGON MARTE MD1, and FRANZ HALBERG MD1

1 Departments of Anesthesiology and Pathology, University of Minnesota College of Medical Sciences, Minneapolis, Minnesota

The mortality of mature, male B1 mice upon exposure to 35 pei cent Fluothane in oxygen for 10 minutes may be as low as 5 per cent or as high as 76 per cent, depending upon the organism's circadian system phase, Predictably penodic changes in susceptibility can be found in test animals of several age groups, apart from differences m susceptibility as a function of age Further consideration of the organism's time structure, as revealed by its rhythms, may lead to safer anaesthetic practices

Note:

Condensed from a paper presented at the Western Divisions' Meeting, Canadian Anaesthetists' Society, held in Edmonton, Alberta, in March 1962 Supported by grants from the US Public Health Service [No H-1983 (C-7) and No 5-K6-GM-13981-03, NB-04531-02], The American Cancer Society (No E-155E), and the Graduate School of the University of Minnesota






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1964 by the Canadian Anesthesiologists' Society.