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Canadian Journal of Anesthesia, Vol 12, 192-196, Copyright © 1965 by Canadian Anesthesiologists' Society
1 Departments of Pharmacology and Anaesthesia, University of Alberta, Edmonton, Alta
A pulsed direct electrical current was applied to the heads of adult dogs through palladium electrodes. These were located on the posterior hard palate and inion, or between the eyes and just behind the inion. In the latter instance a plaster cast was used to keep the electrodes in position. Prior to the current application the animals were sedated with thiopentone, or, ina few cases, with a combination of fentanyl and droperidol.
Currents used were 100 c p s 1 ms to a maximum of 125 ma, 100 c p s 2 ms to a maximum of 37 ma, 200 c p s 2 ms to a maximum of 50 ma, 200 c p s 1 ms to a maximum of 42 ma, random noise in the range 20 kc or 500 kc to a peak of 33 ma. A vanety of currents produced a relaxed quiescent animal but analgesia could not be demonstrated An increase in current produced muscular spasticity.
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