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Canadian Journal of Anesthesia, Vol 12, 331-336, Copyright © 1965 by Canadian Anesthesiologists' Society

Studies Of Pentazocine (WIN-20228). I Evaluation as an Analgesic in Post-Operative Patients

R. A. GORDAN MD, FRCP(C), FFARCS1 and J. H. MORAN MD,DA(TOR),FRCP(C)1

1 Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas

Pentazocine (WIN –20228) is a derivative of the benzmorphan series of drugs It is reported to combine analgesic and narcotic antagonist properties,and is regarded as being free of liability to addiction The effectiveness of pentazocme as an analgesic agent in post-operative patients was established in a randomized blund study in which the drug was compared with equipotent doses of morphine and meperidine In this study there appears to be no difference in the incidence of unwanted side effects produced by the three drugs,such side effects were so rare as to make statistical analysis of any differences completely unprofitable






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Copyright © 1965 by the Canadian Anesthesiologists' Society.