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Canadian Journal of Anesthesia, Vol 13, 21-27, Copyright © 1966 by Canadian Anesthesiologists' Society

A Demonstration of the Site of Action of Intravenous Lignocaine

S. A. FLEMING B.A., M.D., F.F.A.R.C.S.1, J. A. VEIGA-PIRES M.D., C.H.D., D.M.R.D., D.R.D.1, R. M. McCUTCHEON M.D.1, and C. I. EMANUEL M.B., B.S.1

1 Departments of Anaesthesia and Radiodiagnosis, University of Lagos Medical School, Lagos, Nigeria

The intravenous injection of lignocaine distal to a tourniquet has been found a useful, time-saving, safe method of anaesthesia for short operations on a limb. There has been some controversy concerning the site of action of the agent.

A solution of lignocaine containing Hypaque as a radio-opaque medium was used to permit radiological demonstration of the distribution of the solution injected into the veins of the arm distal to the tourniquet. X-ray pictures of the injected limb were correlated with the area of anaesthesia existing at the time of the X-ray exposure, and it was shown that anaesthesia existed only in those areas where the radio-opaque medium was demonstrated actually in the tissues. Anaesthesia spread as the radio-opaque material spread into further tissue. It would seem to be conclusively shown that intravenous lignocaine injected distal to a tourniquet acts at the tissue level on the nerve endings. This would explain the clinical observation of areas of analgesia and complete preservation of sensation existing in the distribution of the same nerve.






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Copyright © 1966 by the Canadian Anesthesiologists' Society.