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Canadian Journal of Anesthesia, Vol 13, 368-373, Copyright © 1966 by Canadian Anesthesiologists' Society

A Comparison of the Action of Meperidine and Diazepam in Anaesthetic Premedication

A. CORMIER M.D., F.R.C.S.(C)1, M. GOYETTE M.D.1, M. KEÉRI-SZÁNTÓ M.D.1, and J. RHEAULT M.D.1

1 Departments of Anaesthesiology and Obstetrics and Gynecology, Notre-Dame Hospital, Montreal

Reprint requests should be directed to M. Keéri-Szántó, Dept. of Anaesthesiology, Notre-Dame Hospital, Montreal 24.

The premedicant action of diazepam was compared with meperidine in a double-blind study involving 160 patients. Sixty patients underwent D & C; the other 100 had laparotomies.

The results indicate that satisfactory premedication can be obtained in most patients by prescribing the drugs at 0700 hours regardless of the hour of surgery. The two compounds produced no statistically significant difference in any of the major parameters by which the success of premedication could be judged. What difference was observed, however, tended to favour diazepam.






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Copyright © 1966 by the Canadian Anesthesiologists' Society.