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Canadian Journal of Anesthesia, Vol 13, 505-512, Copyright © 1966 by Canadian Anesthesiologists' Society

A Clinical Comparison of Propanidid and Thiopentone as Induction Agents to General Anaesthesia

J. E. WYNANDS M.D., C.M.1 and G. S. FOX M.D., F.R.C.P.(C)1

1 Department of Anaesthesia, Royal Victoria Hospital, Montreal, Quebec

Experience with 200 cases, using 2.5 per cent thiopentone as an induction agent in 100 cases, and 5 per cent propanidid (FBA 1420) in the remainder, have been presented. Patients were compared during the induction, peroperative, emergence, and postoperative periods. A greater degree of hypotension, tachycardia, hyperpnoea, and apnoea were seen during induction with propanidid. Postoperatively, patients induced with thiopentone were drowsier, but had a smaller incidence of headache, nausea, and vomiting than those induced with propanidid. Patients in, both groups returned to activity in comparable time periods.

Note:

Presented at the Annual Meeting, Canadian Anaesthetists' Society, Banff, Alberta, June 1966.







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Copyright © 1966 by the Canadian Anesthesiologists' Society.