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Canadian Journal of Anesthesia, Vol 14, 358-364, Copyright © 1967 by Canadian Anesthesiologists' Society

Clinical Experience with PLV-2 (Octapressin) as a Local Haemostatic Agent

DEIRDRE M. M. GILLIES M.B., CH.B.1 and WILLIAM J. FARLEY M.D., F.R.C.P.(C)1

1 Department of Anaesthesia, Queen Elizabeth Hospital of Montreal and McGill University

The purpose of this study is to assess the value of PLV-2 (Octapressin) as a local haemostatic agent used in conjunction with various common general anaesthetic agents and techniques. It has been used in 206 surgical procedures to improve surgical visibility and to reduce blood loss. These operations fall in three main groups: gynaecology by the vaginal route, lumbar discoidectomy, and tonsillectomy in children and adults. In order to assess the compatibility of PLV-2 with cyclopropane, halothane, and methoxyflurane, cardiac action has been monitored in the majority of cases.

It is concluded that PLV-2 is a valuable adjunct to vaginal surgery, blood loss being reduced to a minimum and visibility so improved that surgery can oe accomplished with greater accuracy and speed. When PLV-2 is used in nose and throat cases, its effects are not impressive; the reasons for this are not clear. PLV-2 does not appear to have significant systemic effects when used in this manner. It appears to be compatible with the anaesthetic agents used in this study.






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Copyright © 1967 by the Canadian Anesthesiologists' Society.