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Canadian Journal of Anesthesia, Vol 14, 519-542, Copyright © 1967 by Canadian Anesthesiologists' Society

Effets De Certains Agents Anesthesiques Sur L'activite Electrique Cerebrale

G. VOURC'H M.D.1, G. ARFEL M.D.2, and J. M. BESSON M.D.3

1 Faculté de médecine, Paris, et Chef du service d'anesthésie, Hôopital Foch, Suresnes Seine
2 I.N.S.E.R.M., et Chef du laboratoire d'électroencéphalographie, Hôpital Foch, Suresnes Seine
3 C.N.R.S., et avec le Centre d'études de physiologie nerveuse, Paris

Within a systematic investigation of the action of the general anaesthetic agents on cerebral structures, we have studied, on one hand, the modifications produced by circulatory and respiratory changes and also the action of anaesthetic agents: i.v. short acting, morphine, and morphino-mimetics on the animal; on the other hand, we have studied the action of some neuroleptics on man.

The results obtained have been applied clinically in the surgical treatment of Parkinson's disease, in certain kinds of epilepsy, and in topectomies for intractable pain under neurophysiological control. An appropriate choice of anaesthetic drugs allows one to obtain satisfactory operative conditions and at the same time permits a correct record of the evoked and spontaneous activities in explored cerebral structures.






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Copyright © 1967 by the Canadian Anesthesiologists' Society.