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Canadian Journal of Anesthesia, Vol 15, 227-231, Copyright © 1968 by Canadian Anesthesiologists' Society
1 Departments of Anaesthesia and Neurosurgery, University of Toronto and Toronto General Hospital
A comparative evaluation has been made of the effects of different anaesthetic agents and techniques upon the mortality of patients undergoing intracranial surgery for ruptured intracranial aneurysms. No statistically significant difference was noted when comparing groups in which halothane or trichlorethylene was the main anaesthetic agent. Neither was there any difference in mortality in groups in which halothane was used with or without controlled ventilation. It is concluded that variation in agent or method of general anaesthesia, which should on theoretical grounds result in differences in cerebral blood flow, has not affected postoperative mortality rates either adversely or beneficially.
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