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Canadian Journal of Anesthesia, Vol 15, 325-331, Copyright © 1968 by Canadian Anesthesiologists' Society
1 Department of Anaesthesia, University of Toronto
A helium dilution method of measuring FRC under conditions of controlled ventilation is described. Using this method the effect on FRC of premedication and of induction of anaesthesia and muscle paralysis has been investigated. No significant change in FRC was found with premedication alone. A significant fall (p < .01) was observed with the induction of anaesthesia and muscle paralysis. The combined effect of premedication and induction of anaesthesia and muscle paralysis also produced a significant fall in FRC (p < .05).
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