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Canadian Journal of Anesthesia, Vol 16, 225-234, Copyright © 1969 by Canadian Anesthesiologists' Society

The Role of Replacement Fluids in the Management of Haemorrhagic Shock: An Experimental Study

R. RAJAGOPALAN M.D.(ANAESTH.)1, G. C. TANDAN F.F.A.R.C.S.(ENG. ), F.A.M.S.1, and G. R. GODE F.F.A.R.C.S.(ENG.)1

1 All India Institute of Medical Sciences, New Delhi, India

An experimental study was undertaken in 32 healthy mongrel dogs to evaluate the comparative usefulness of blood, lactated Ringer's solution, dextran, and low molecular weight dextran in the management of haemorrhagic shock. Changes in mean arterial pressure, central venous pressure, acid-base state, and survival rate were studied and compared.

Lactated Ringer's solution was found to be a promising replacement fluid, ranking next to blood. It increased central venous pressure and controlled the metabolic acidosis.

Continuous central venous pressure monitoring was found to be a more reliable guide than mean arterial pressure monitoring in the management of shock. Changes in the central venous pressure correlated well with the survival rate and the state of metabolic acidosis.

Note:

From the Department of Anaesthesiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 16, India.






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Copyright © 1969 by the Canadian Anesthesiologists' Society.