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Canadian Journal of Anesthesia, Vol 16, 302-308, Copyright © 1969 by Canadian Anesthesiologists' Society

Peripheral Haemodynamic Effects of Electronarcosis

WALTER H. MASSION M.D.1 and PAULA DOWNS 1

1 Department of Anesthesiology, University of Oklahoma Medical Center, Oklahoma City, Oklahoma

The effects of electronarcosis on peripheral haemodynamics were studied in the isolated forelimb preparation of the dog. Forelimbs of dogs under nembutal anaesthesia were severed from the body and perfused at constant flow rate by a Sigma motor pump with blood drawn from animals under electronarcosis. It was found that blood from animals under electronarcosis consistently caused vasoconstriction in the isolated forelimb which could be blocked partially by phentolamine. It is concluded that electronarcosis causes the release of vasoactive substances into the circulation, the bulk of which appear to be catecholamines.

Note:

Dr. Massion is a recipient of USPHS Research Career Development Grant 5-K3-GM-17.651






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Copyright © 1969 by the Canadian Anesthesiologists' Society.