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Canadian Journal of Anesthesia, Vol 16, 477-486, Copyright © 1969 by Canadian Anesthesiologists' Society

Positive Expiratory Pressure Plateau: Improved Gas Exchange During Mechanical Ventilation

R. W. McINTYRE M.B., CH.B., D.A., F.R.C.P.(C)1, A. K. LAWS B.SC, M.B., B.S., F.F.A.R.C.S.1, and P. R. RAMACHANDRAN M.B., B.S., F.R.C.P.(C)1

1 Department of Anaesthesia, University of Toronto, and the Toronto General Hospital

The effect of a positive expiratory pressure plateau (pepp) on gas exchange, cardiac output, and frc is examined in five patients in severe respiratory failure receiving artificial ventilation. Improvement in gas exchange for both oxygen and carbon dioxide without change in cardiac output is demonstrated in all cases. This is associated with an increase in resting lung volume. The mechanisms and therapeutic implication of these changes are discussed. It is suggested that this feature of the ventilatory wave form may be of considerable value in the management of severe hypoxia during respiratory failure.

Note:

Presented at the Annual Meeting, Canadian Anaesthetists' Society, Toronto, June 17, 1969.






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Copyright © 1969 by the Canadian Anesthesiologists' Society.