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Canadian Journal of Anesthesia, Vol 17, 61-69, Copyright © 1970 by Canadian Anesthesiologists' Society

Comparison of the Cardiovascular and Respiratory Effects of Light General Anaesthesia and Brachial Plexus Block

WILLIAM F. KENNEDY JR. M.D.1, JOHN J. BONICA M.D.1, ANDREW G. TOLAS D.D.S.2, WAYNE E. MARTIN M.D.3, and ALEXANDER GRINSTEIN M.D.4

1 Department of Anesthesiology, University of Washington School of Medicine, Seattle, Washington
2 Departments of Anesthesiology and Oral Surgery, University of Washington Schools of Medicine and Dentistry
3 the Department of Anesthesiology, University of Washington School of Medicine, Seattle, Washington
4 Cobb Medical Center, Seattle, Washington

Brachial plexus block with epinephrine (1:200,000) and general anaesthesia with halothane-nitrous oxide-oxygen in the same individual were compared. The brachial plexus block with epinephrine produced statistically significant changes in cardiac rate, cardiac output, stroke volume, and calculated total peripheral resistance. These effects were due to the epinephrine incorporated in the local anaesthetic solution. General anaesthesia with halothane-nitrous oxide produced significant decrease in the mean arterial pressure and total peripheral resistance. On the basis of cardiovascular and respiratory effects, brachial plexus block is considered to be preferable for surgery of the upper extremity.

Note:

Supported by US Army Research and Development Command, Office of the Surgeon General, Contract DA 49-193-MD-2231.






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Copyright © 1970 by the Canadian Anesthesiologists' Society.