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Canadian Journal of Anesthesia, Vol 17, 269-274, Copyright © 1970 by Canadian Anesthesiologists' Society

Bronchial Spasm During General Anaesthesia

VICTOR BRANDUS M.D.1, SARAH JOFFE M.D.1, CHARLES V. BENOIT M.D.1, and WILLIAM I. WOLFF M.D.2

1 Department of Anesthesia Beth Israel Medical Center, New York, N.Y.
2 Department of Surgery, Beth Israel Medical Center, New York, N.Y.

Reprint requests should be sent to Dr. Brandus at Beth Israel Medical Center, Department of Anesthesia, New York, N.Y. 10003

Two cases of severe bronchial spasm in patients under general anaesthesia are presented. In the first case the bronchial spasm, according to our clinical impression, was due to histamine release following a rapid intravenous injection of 15 mg of d-tubocurarine; 100 mg of lignocaine, administered intravenously, abolished the spasm. In the second case the spasm was induced reflexly by the intubation of the trachea in a patient under thiopentone anaesthesia; 40 mg of procaine, intravenously, ended the attack. The possible mechanisms by which local anaesthetic drugs may induce relaxation of the bronchial muscle are discussed.






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Copyright © 1970 by the Canadian Anesthesiologists' Society.