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Canadian Journal of Anesthesia, Vol 17, 341-346, Copyright © 1970 by Canadian Anesthesiologists' Society

Effect of Methoxyflurane on Epinephrine-Induced Ventricular Arrhythmias

BRUCE W. BURLEIGH M.D.,1 and NICHOLAS M. GREENE M.D.,1

1 Division of Anesthesiology, Yale University School of Medicine, and the Department of Anesthesiology, Yale New Haven Medical Center, New Haven, Connecticut

Address reprint requests to Dr. Nicholas M. Greene, 789 Howard Ave., New Haven, Conn. 06504.

Methoxyflurane anaesthesia in dogs had no significant effect on time of onset or duration of ventricular arrhythmias produced by continuous infusion of epinephrine. It is concluded that methoxyflurane neither protects nor sensitizes the canine myocardium to epinephrine. It is suggested that methoxyflurane is the inhalation anaesthetic of choice when epinephrine is employed.

Note:

Dr. Burleigh was a medical student research fellow while carrying out this research.






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Copyright © 1970 by the Canadian Anesthesiologists' Society.