CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by STEPHEN, C. R.
Right arrow Search for Related Content
PubMed
Right arrow Articles by STEPHEN, C. R.

Canadian Journal of Anesthesia, Vol 17, 403-410, Copyright © 1970 by Canadian Anesthesiologists' Society

Premedication with Droperidol: A Double-Blind Study

C. R. STEPHEN M.D.,1

1 Department of Anesthesiology, University of Texas (Southwestern) Medical School, and Parkland Memorial Hospital, Dallas, Texas

1. In a double-blind study involving 514 adult patients, a comparison was made of the effectiveness and safety of droperidol and secobarbital as premedicant drugs prior to anaesthesia and surgery.

2. The three groups studied (the third group receiving a placebo) had a homogeneity of distribution which gives credence to the results.

3. Subjectively, droperidol produced drowsiness in a significantly larger number of patients, statistically, than did secobarbital or the placebo.

4. Objectively, droperidol was rated as providing good sedation in a significantly larger percentage of patients, statistically, than received secobarbital or the placebo.

5. Untoward effects on the respiratory or cardiovascular systems were not seen following either of the premedicant drugs employed.

6. Droperidol is believed to be a useful, safe, and effective drug for premedication.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1970 by the Canadian Anesthesiologists' Society.