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Canadian Journal of Anesthesia, Vol 17, 551-556, Copyright © 1970 by Canadian Anesthesiologists' Society

The Effect of Hypothermia on the Respiratory Response to Carbon Dioxide

GERALD EDELIST M.D.1

1 Department of Anaesthesia, University of Toronto and New Mount Sinai Hospital, Toronto

The primary effect of hypothermia on the respiratory response to carbon dioxide, studied in five dogs, is shown to be a shift of the CO2 response curve to the left with no significant change in the slope. If one does not take into account the fact that anaesthesia deepens during hypothermia for the same concentration of anaesthetic inhaled, then the slope of the CO2 response curve becomes markedly depressed. This may be the reason for the clinical impression of some observers that hypothermia depresses ventilation.






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Copyright © 1970 by the Canadian Anesthesiologists' Society.