CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by STANIWESKI, J. A.
Right arrow Articles by ALDRETE, J. A.
Right arrow Search for Related Content
PubMed
Right arrow Articles by STANIWESKI, J. A.
Right arrow Articles by ALDRETE, J. A.

Canadian Journal of Anesthesia, Vol 17, 602-606, Copyright © 1970 by Canadian Anesthesiologists' Society

The Effects of Inhalation Anaesthetic Agents on Convulsant (LD-50) Doses of Local Anaesthetics in the Rat

JOHN A. STANIWESKI B.A.1 and J. ANTONIO ALDRETE M.D.1

1 Department of Anesthesiology, University of Miami School of Medicine, P.O. Box 875, Biscayne Annex, Miami, Florida

The inhalation of low concentrations of anaesthetic mixtures by rats appeared to provide protection from the obvious convulsions produced by intraperitoneal injections of LD-50 doses of local anaesthetic drugs. However, higher concentrations enhanced the lethal effects of procaine, lidocaine, and tetracaine, probably by a summation of their depressive action on the cardiac and respiratory functions.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1970 by the Canadian Anesthesiologists' Society.