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Canadian Journal of Anesthesia, Vol 17, 607-612, Copyright © 1970 by Canadian Anesthesiologists' Society

Anaesthetic Dosage for Epidural Sympathetic Blockade

P. Y. CHEN M.D.1 and CLOID D. GREEN M.D.2

1 New England Medical Center Hospital, Tufts University School of Medicine, 171 Harrison Avenue, Boston, Massachusetts 02111, U.S.A.
2 Department of Anesthesia, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada

The anaesthetic dose for epidural sympathetic block was determined by the objective method of the PGR in a group of surgical patients. It was found that 10 ml of 0.375 per cent lidocaine with epinephrine (1:200,000) was the median effective dose (ED50) in six patients; however, we concluded that 10 ml of 0.5 per cent lidocaine with epinephrine was the minimal concentration which can be reliably used clinically to produce sympathetic block by the epidural route.

The onset and duration of sympathetic block produced by 10 ml of lidocaine, 0.5 per cent and 1.0 per cent concentrations with epinephrine were also studied.






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Copyright © 1970 by the Canadian Anesthesiologists' Society.