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Canadian Journal of Anesthesia, Vol 19, 615-622, Copyright © 1972 by Canadian Anesthesiologists' Society

A Clinical Comparison of Pancuronium Bromide with D-Tubocurarine in Adult Nigerian Patients

J.A. O. MAGEABEOLA M.B., CH.B.(BRIST.), F.F.A.R.C.S.L.1

1 Department of Anaesthesia, University of Ibadan, Ibandan, Nigeria

The effects of pancuronium bromide and d-tubocurarine were investigated on 160 Nigerian patients in the dose of 0.1 mg/kg body weght respectively. The onset of action of pancuronium bromide was more rapid than that of d-tubocurarine while the duration of action of the two drugs was similar. The blood pressure and pulse rate were maintained even when halothane was employed with pancuronium. d-tubocurarine on the other hand caused hypotension which was more severe in the presence of halothane. The rapid onset of action of pancuronium bromide made intubation 60 seconds after injection easier. No skin reaction was observed with pancuronium bromide.






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Copyright © 1972 by the Canadian Anesthesiologists' Society.