CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by COOK, D. R.
Right arrow Articles by HAMMONDS, M. W.
Right arrow Search for Related Content
PubMed
Right arrow Articles by COOK, D. R.
Right arrow Articles by HAMMONDS, M. W.

Canadian Journal of Anesthesia, Vol 19, 634-638, Copyright © 1972 by Canadian Anesthesiologists' Society

Potassium Release following Administration of Succinylcholine in Chronically Uraemic Monkeys

DAVID R. COOK M.D.1, A. BENEDICT COSIMI M.D.1, and MAX W. HAMMONDS M.D.1

1 Department of surgery, Anesthesiology Servics and General Surgery Service, Wilford Hall USAF Medical Center, Lackland Air Force Base, Texas 78236

The change in potassium response following succinylcholine was studied in eleven Rhesus monkeys after 10 and 20 days of persistent uraemia. We noted no significant increase in mean potassium levels after administration of succinylcholine in the uraemic groups when contrasted with a control group. However, the serum potassium in one animal rose 1.7 mEq/liter, which is a significant rise (P < 0.05). The potassium response did not change with increasing duration of uraemia, nor did it correlate with either the degree of uraemia nor with the initial potassium value. Since it is impossible to predict under what circumstances an exaggerated response may occur we advise continued caution in the use of succinylcholine in uraemic patients.

Note:

Major. USAF, MC, Staff Anaesthesiologist.

Major, USAF, Staff General Surgeon.

Captain, USAF, MC, Resident in Anesthesiology.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1972 by the Canadian Anesthesiologists' Society.