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Canadian Journal of Anesthesia, Vol 2, 178-183, Copyright © 1955 by Canadian Anesthesiologists' Society

Factors affecting Trichlorethylene Vapour Concentrations

A. W. CONN M.D.1, A. E. DYER M.A.2, and J.K. W. FERGUSON M.D.2

1 Department of Pharmacology, University of Toronto, and the Hospital for Sick Children, Toronto, Canada
2 Department of Pharmacology, University of Toronto

The trichlorethylene vapour concentrations dehveied by a standard anaesthetic machine were determined at room temperature and atmospheric pressure. The effect on these concentrations by changes in valve opening, rate of gaseous flow, fluid volume, and liquid temperature was observed and discussed.

It was shown that with valve openmg 4, a progressive fall in vapour concentration occurred from a high initial level. At this valve setting, the concentration tended to decrease as gaseous flow was mcreased, and to rise as the fluid level was increased. A decrease in liquid temperature appeared to have little effect on vapour concentration, which is in marked contrast to the known effect of temperature on ether concentrations.

The vapour concentrations attained with valve opening 4 are too high for continuous clinical use. Since these high concentrations are always associated with bubbling of the gas through the tnchlorethyleae, it is suggested that "bubbling" be avoided during anaesthesia.

The vapour concentrations increased as the valve was opened from 1 to 3. At each valve setting, the initial concentration remained almost constant despite changes in gaseous flow rate, fluid volume, and liquid temperature. A slight increase in concentration occurred if a surface disturbance was created. The vapour concentrations attained with valve openings 1, 2, and 3 are within the clinical range.






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Copyright © 1955 by the Canadian Anesthesiologists' Society.