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Canadian Journal of Anesthesia, Vol 21, 79-82, Copyright © 1974 by Canadian Anesthesiologists' Society

The Use of Pancuronium Bromide in Patients Receiving Lithium Carbonate

HERMAN BORDEN M.D.1, MAXINE T. CLARKE M.D.1, and HERZL KATZ M.D.1

1 Saint John's Hospital, 1328 22nd Street, Santa Monica, California 90404

A surgical patient receiving lithium carbonate therapy is presented, in whom the use of the non-depolarizing muscle relaxant pancuronium bromide produced prolonged neuromuscular blockade. Possible mechanism of action involves impaired ACH synthesis and release. The physiology and pharmacology of lithium bromide are discussed.






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Copyright © 1974 by the Canadian Anesthesiologists' Society.