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Canadian Journal of Anesthesia, Vol 22, 339-348, Copyright © 1975 by Canadian Anesthesiologists' Society

The Cardiovascular Effects of Ketamine in Hypotensive States

DAVID H. W. WONG 1 and LEONARD C. JENKINS 1

1 Department of Anaesthesia and Experimental Research Laboratory, Faculty of Medicine, University of British Columbia

Ketamine was found to raise the systemic arterial blood pressure but not necessarily the perfusion in hypovolaemic states. However, in hypotensive states of short duration from endotoxin treatment, it improved the haemodynamics with increase in both the perfusion and the systemic pressure. The implications of these observations for clinical situations were discussed.






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Copyright © 1975 by the Canadian Anesthesiologists' Society.