CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by OYAMA, T.
Right arrow Articles by MAKI, M.
Right arrow Search for Related Content
PubMed
Right arrow Articles by OYAMA, T.
Right arrow Articles by MAKI, M.

Canadian Journal of Anesthesia, Vol 22, 349-357, Copyright © 1975 by Canadian Anesthesiologists' Society

The Coagulation-Fibrinolysis System in Man During Ethrane® Anaesthesia and Surgery

T. OYAMA 1, M. TAKIGUCHI 1, M. NAGAYAMA 1, and M. MAKI 1

1 Department of Anaesthesia, Hirosaki University School of Medicine, Hirosaki, Aomori-Ken, Japan

The coagulation-fibrinolysis system was studied during Ethrane® anaesthesia and gynaecological operations in 20 patients.

No particular change was noted in the platelet counts, which remained within the normal range. In the coagulation system, no appreciable change was observed except for the partial thromboplastin time( P.T.T.) which was significantly shortended, both 30 minutes after the start of operation and in the recovery room when the patient had completely awakened from the anaesthesia.

In the fibrinolytic system, the plasminogen level and the fibrinogen level declined significantly.

It is considered that the fibrinolytic system is prominently accelerated under Ethrane® anaesthesia, but the haemostatic mechanism works in such a manner that bleeding is controlled. However, Ethrane® anaesthesia should be avoided or pre-operative administration of an antiplasmic agent recommended for patients with an abnormal haemostatic mechanism.

Note:

Present address: Anaesthesiology Service/112A, Veterans Administration Center, Wood (Milwaukee), Wisconsin 53193.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1975 by the Canadian Anesthesiologists' Society.