CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by OBDRZALEK, J.
Right arrow Articles by NOBLE, W. H.
Right arrow Search for Related Content
PubMed
Right arrow Articles by OBDRZALEK, J.
Right arrow Articles by NOBLE, W. H.

Canadian Journal of Anesthesia, Vol 22, 399-409, Copyright © 1975 by Canadian Anesthesiologists' Society

The Effects of Continuous Positive Pressure Ventilation on Pulmonary Oedema, Gas Exchange and Lung Mechanics

JIRI OBDRZALEK 1, J. COLIN KAY 1, and WILLIAM H. NOBLE 1

1 Department of Anaesthesia, St. Michael's Hospital and University of Toronto, Toronto, Ontario, Canada

The effect of continuous positive pressure ventilation was studied in 23 dogs in whom pulmonary oedema was induced by rapid intravenous infusion of dextran 40. CPPV slowed but did not prevent the formation of oedema.

CPPV prevented or reversed the formation of liver-like areas in the dependent lobes, maintaining the oedematous lung compliant and aerated. This led to a reduction of shunt and an increase in PaO2. The use of CPPV decreased cardiac output and body oxygen consumption. Mixed venous oxygen tension was higher in dogs ventilated by CPPV and these dogs tolerated fulminant frothy oedema without distress.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1975 by the Canadian Anesthesiologists' Society.