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Canadian Journal of Anesthesia, Vol 22, 432-435, Copyright © 1975 by Canadian Anesthesiologists' Society

The Effect of Artificial Ventilation on Functional Residual Capacity and Arterial Oxygenation

II Comparison of Spontaneous Respiration and Artificial Ventilation at Similar Arterial Carbon Dioxide Tensions, Tidal Volumes and Inspiratory Gas Flow Rates

D. S. ARTHUR 1, A. K. MATHUR 1, H.I. A. NISBET 1, and G. A. VOLGYESI 1

1 Department of Anaesthesia, Research Institute, Hospital for Sick Children, Toronto, and the University of Toronto, Toronto, Ontario, Canada

We have compared cardiac output, gas exchange and pulmonary mechanics during spontaneous breathing and artificial ventilation under conditions which kept PaCOCO2 within the normal range and maintained constant tidal volume and inspired gas flow rate.

In dogs anaesthetized with pentobarbitone and ventilated with air, artificial ventilation increased VD/VT but did not reduce Q·, FRC, or CL. PaOO2 increased and A-aDOO2 decreased during artificial ventilation, perhaps because of a small increase in Q· and a small decrease in oxygen consumption. It appears that many of the reported deleterious effects of artificial ventilation may be due to the use of other anaesthetic agents and patterns of ventilation, and to changes in PaCOCO2.






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Copyright © 1975 by the Canadian Anesthesiologists' Society.