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Canadian Journal of Anesthesia, Vol 23, 15-21, Copyright © 1976 by Canadian Anesthesiologists' Society

Patterns of Total and Ionized Calcium and Other Electrolytes in Plasma During and After General Surgery

R. RODRIGUEZ 1, R. R. JONES , M. A. ADSON , and E. A. MOFFITT 2

1 Departments of Anesthesiology and Surgery, Mayo Clinic and Foundation, Rochester, Minn., U.S.A.
2 Department of Anaesthesia, Dalhousie University, Halifax, Nova Scotia

Thirteen patients were studied during two hours of anaesthesia for abdominal operations and for an hour post-operatively. Serial venous blood samples were taken for determination of plasma total and ionized calcium, acid-base variables, Na, K, Mg, PO4 total proteins and parathyroid hormone. One group of patients received 5 per cent dextrose/water and the other 5 per cent dextrose in Ringer's solution, at 250 ml per hour. Total and ionized calcium levels decreased toward the end of operation and an hour later, associated with respiratory alkalosis. Parathyroid hormone increased at the end of operation, as an effect of the decreased ionized calcium. The general effect was mild haemodilution with all the other electrolytes decreasing, as did total protein concentration.






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Copyright © 1976 by the Canadian Anesthesiologists' Society.