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Canadian Journal of Anesthesia, Vol 23, 307-318, Copyright © 1976 by Canadian Anesthesiologists' Society

Inhibition of the Cardiovascular Effects of Acupuncture (Moxibustion) by Propranolol in Dogs during Halothane Anaesthesia

D. C. LEE 1, M. O. LEE 1, D. H. CLIFFORD 1, and L. E. MORRIS 1

1 Departments of Anaesthesia, Physiology and Anatomy and the Division of Laboratory Animal Medicine, Medical College of Ohio, Toledo, Ohio 43614, U.S.A.

Acupuncture by electrocautery, moxibustion, at Jen Chung (Go-26) acupoint produces a sympathomimetic effect on the cardiovascular system of dogs under halothane anaesthesia (MAC I). This effect is manifest by significant increase in cardiac output, stroke volume, heart rate, mean arterial pressure and pulse pressure while total peripheral resistance is significantly decreased during a two-hour period of observation. Pretreatment with the beta blocker, propranolol, caused a significant decrease in cardiac output, heart rate, mean arterial pressure and pulse pressure while total peripheral resistance is significantly increased. Similar responses were observed when propranolol was administered without moxibustion at Jen Chung (Go-26).

Note:

Supported in part by GRS Grant #5-S01 RR 05700-04 and the Northwestern Ohio Heart Association.






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Copyright © 1976 by the Canadian Anesthesiologists' Society.