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Canadian Journal of Anesthesia, Vol 24, 586-596, Copyright © 1977 by Canadian Anesthesiologists' Society

Maternal and Neonatal Effects of Methoxyflurane, Nitrous Oxide and Lumbar Epidural Anaesthesia for Caesarean Section

RICHARD J. PALAHNIUK 1, JOHN SCATLIFF 1, DIANE BIEHL 1, HENRY WIEBE 1, and K. SANKARAN 1

1 Departments of Anaesthesia and Paediatrics, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba, Canada

Address reprint requests to Dr. R. J. Palahniuk, Department of Anaesthesia, Health Sciences Centre, 700 William Avenue, Winnipeg, Canada, R3E 0Z3.

General anaesthetic techniques continue to be used for Caesarean section despite the possible increased incidence of foetal acidosis and neonatal depression. Two techniques of general anaesthesia (methoxyflurane-oxygen and nitrous oxide-oxygen) and lumbar epidural anaesthesia were compared in 37 patients undergoing elective Caesarean section. Apgar scores at birth were similar in all three groups. Neurophysiological testing of the neonates at six hours and twenty-four hours of age revealed a superiority for the methoxyflurane-oxygen and lumbar epidural techniques, although the babies in the epidural group tended to be hypo-tonic. Cord blood gas analysis showed the babies in the methoxyflurane group to have a higher PaOO2 with less metabolic acidosis than the babies from the other two groups. The maternal effects of the three anaesthetic techniques were similar, with only a small rise in serum fluoride levels noted in the methoxyflurane group.

Note:

Presented at the American Society of Anesthesiologists' Meeting, San Francisco, October, 1976. Supported, in part, by a grant from Abbott Laboratories, Montreal, Quebec.






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Copyright © 1977 by the Canadian Anesthesiologists' Society.