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Canadian Journal of Anesthesia, Vol 24, 712-716, Copyright © 1977 by Canadian Anesthesiologists' Society

Effect of Etomidate on Intra-Ocular Pressure

C. E. FAMEWO M.B., B.S., Dip. Anaes., F.R.C.P.(C)1, C. O. ODUGBESAN M.D., Dip. Anaes., F.R.C.P.(C)1, and O. O. OSUNTOKUN M.B., B.S., D.O., F.M.C.S.(Ophth.)2

1 Department of Anaesthesia, University College Hospital, Ibadan, Nigeria
2 Department of Ophthalmology, University College Hospital, Ibadan, Nigeria

Etomidate, a new short-acting non-barbiturate hypnotic, was administered to 40 patients between the ages of 12 years and 65 years. Intra-ocular pressure was measured before and after etomidate injection using a Schiotz tonometer. A significant reduction of intra-ocular pressure was found to follow etomidate injection in spite of the often associated myoclonic movements. The mechanism of reduction of intra-ocular pressure has not been determined in this study. It is suggested that etomidate will be a useful intravenous induction agent where elevation of intra-ocular pressure is undesirable.






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Copyright © 1977 by the Canadian Anesthesiologists' Society.