CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by CANDY, J. J.
Right arrow Articles by McQUEEN, M. J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by CANDY, J. J.
Right arrow Articles by McQUEEN, M. J.

Canadian Journal of Anesthesia, Vol 25, 53-59, Copyright © 1978 by Canadian Anesthesiologists' Society

Succinylcholine Sensitivity In A Nova Scotia Family

J. J. CANDY 1 and M. J. McQUEEN 2

1 Department of Anaesthesia, Dalhousie University, Halifax
2 Clinical Chemistry, Hamilton General Hospital, Hamilton, Ontario

Succinylcholine apnoea is usually the result of a delay in hydrolysis of the injected muscle relaxant due to the presence of an inherited defect in the enzyme cholinesterase

This report presents a Nova Scotia family in whom several members had "difficulty in breathing" following anaesthesia. Subsequent investigations revealed the presence of several phenotypes of the enzyme cholinesterase including individuals who were homozygous for the atypical cholinesterase genes.

The frequency of occurrence and significance of the various phenotypes are discussed, together with their management and recommendations for family screening.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1978 by the Canadian Anesthesiologists' Society.