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Canadian Journal of Anesthesia, Vol 25, 113-116, Copyright © 1978 by Canadian Anesthesiologists' Society

Cardiovascular Haemodynamics during Enflurane-Pancuronium Anaesthesia in Patients with Valvular Heart Disease

PETER VALDEMAR KLAUBER 1, MOGENS BREDGAARD SØRENSEN 1, VINNI CHRISTENSEN 1, FINN WIBERG-JØRGENSEN 1, and PER SKOVSTED 2

1 Department of Anaesthesia, Department of Cardiac Surgery R, and the Surgical Laboratory for Circulation Research D, Rigshospitalct (State University Hospital), Blegdamsvej 9, 2100 Copenhagen, Denmark
2 Department of Anaesthesia, Department of Cardiac Surgery R, and the Surgical Laboratory for Circulation Research D, Rigshospitalet (State University Hospital), Blegdamsvej 9, 2100 Copenhagen, Denmark

The effects of enflurane-pancuronium anaesthesia on cardiovascular haemodynamics were studied before operation in six patients with valvular heart disease. A ten per cent decline in cardiac index and a 20 per cent decline in stroke volume were the only changes observed. Mean arterial, pulmonary arterial, central venous, and pulmonary capillary wedge pressures were unaffected, as were systemic vascular resistance and pulmonary vascular resistance.

The authors therefore conclude that enflurane-pancuronium anaesthesia causes only minimal cardiovascular depression in patients with valvular heart disease.






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Copyright © 1978 by the Canadian Anesthesiologists' Society.