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Canadian Journal of Anesthesia, Vol 26, 435-436, Copyright © 1979 by Canadian Anesthesiologists' Society

Anaphylactoid Reaction to Mannitol

JONATHAN D. LAMB M.D.1 and JOHN A. M. KEOGH 1

1 Department of Anaesthesiology, University Hospital, Saskatoon, Saskatchewan, Canada, S7N 0W8

A 16-year old boy with a lesion of the right eye developed, during the preoperative administration of a mannitol infusion, an anaphylactoid reaction characterized by hypotension, perior-bital oedema and bronchospasm. This quickly resolved following cessation of the infusion and appropriate therapeutic measures. There were no long-lasting effects. We considered mannitol the causative agent because of its temporal relationship to the reaction and our inability to seriously implicate any other medication. A history of childhood atopy may have been a predisposing factor.






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Copyright © 1979 by the Canadian Anesthesiologists' Society.