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Canadian Journal of Anesthesia, Vol 26, 482-483, Copyright © 1979 by Canadian Anesthesiologists' Society

The Effect of Lidocaine on Succinylcholine-Induced Rise in Intraocular Pressure

R. BRIAN SMITH 1, MACIEJ BABINSKI 1, and NAPOLEON LEANO 1

1 Department of Anesthesiology, University of Texas, Health Science Center, 7703 Floyd Curl Drive, San Antonio, Texas, 78284, U.S.A.

The effect of lidocaine on the increase of intraocular pressure induced by succinylcholine was studied in patients 6 to 85 years of age. Three groups of patients were studied. One group of eight patients received lidocaine 1 mg·kg-1 before succinylcholine and a control group of ten patients did not have lidocaine. Anaesthesia was induced with thiopentone 5 mg·kg-1 and maintained with nitrous oxide 50 per cent with oxygen and halothane 1.0-1.5 per cent. The tracheae of all patients were intubated.

Lidocaine in doses of 1.0 to 2.0 mg·kg-1 did not prevent transient rise in intraocular pressure following administration of succinylcholine and tracheal intubation.






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Copyright © 1979 by the Canadian Anesthesiologists' Society.