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Canadian Journal of Anesthesia, Vol 27, 445-448, Copyright © 1980 by Canadian Anesthesiologists' Society

The Effect of Posture on the Ventilatory Response to Hypoxia

A. S. SLUTSKY 1, R. G. GOLDSTEIN 1, and A. S. REBUCK 1

1 Respiratory Care Unit, Toronto General Hospital

Address correspondence to: Dr. A.S. Slutsky, Respiratory Disease Division, Peter Bent Brigham Hospital, 721 Huntington Avenue, Boston, MA, 02115.

The ventilatory response to carbon dioxide is known to be uninfluenced by changes in posture. To obtain similar data on the ventilatory response to hypoxia we studied seven subjects in each of two postures, lying and sitting, at a constant Pcoco2 midway between end-tidal and mixed venous. Minute ventilation was higher in the seated position than supine (p < 0.01) at this isocapnic level, attributable mainly to an increase in tidal volume (p < 0.05). However, there were no statistically significant differences in the ventilatory response, the tidal volume response, or the frequency response to hypoxia between the two postures.






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Copyright © 1980 by the Canadian Anesthesiologists' Society.