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Canadian Journal of Anesthesia, Vol 27, 576-577, Copyright © 1980 by Canadian Anesthesiologists' Society

Surdosage Accidentel En Alfatesine Chez Un Enfant Polymalforme

G. BOULARD 1, G. MIET 1, J. GUERIN 2, and M. SABATHIE 1

1 Hôpital Pellegrin, - 33076 Bordeaux, France
2 Clinique Neuro-Chirurgicale, Hôpital Pellegrin, - 33076 Bordeaux, France

An overdosage of alfathesin was accidentally administered to a 4 kg infant with multiple congenital anomalies during an operation for craniosynostosis. The overdose was a consequence of a mistake in adjusting the rate of administration of a constant flow infusion pump. The total dosage corresponded to eight times the necessary dose administered over a period of 30 minutes.

The only notable effect was a delayed awakening, which necessitated assisted ventilation. The high therapeutic index of alfathesin is responsible for the absence of serious consequences.






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Copyright © 1980 by the Canadian Anesthesiologists' Society.