CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by WEXLER, H. R.
Right arrow Articles by LOK, P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by WEXLER, H. R.
Right arrow Articles by LOK, P.

Canadian Journal of Anesthesia, Vol 28, 370-372, Copyright © 1981 by Canadian Anesthesiologists' Society

A Simple Formula for Adjusting Arterial Carbon Dioxide Tension

H. R. WEXLER 1 and PETER LOK 2

1 Department of Anaesthesia, University of Western Ontario, University Hospital, London, Ontario, Canada
2 Department of Respiratory Technology, University of Western Ontario, University Hospital, London, Ontario, Canada

Address for reprints: Dr. H.R. Wexler, Department of Anaesthesia, University Hospital, P.O. Box 5339, Postal Stn. A., London, Canada. N6A 5A5.

To improve the accuracy of acid-base adjustment in mechanically ventilated patients we derived the formula:

Required minute ventilation = known arterial PCO2 x known minute ventilation/desired arterial PCO2

which allows calculation of the minute ventilation required to produce a desired arterial PCO2 by measuring the patient's existing arterial PCO2 and minute ventilation. This was tested in fifty patients using four types of ventilators and found to be statistically accurate, with a mean difference between predicted and observed PCO2 of 0.153 kPa (1.15 torr) ± S.E.M. 0.798.

Key Words: ACID-BASE EQUILIBRIUM, adjustment • VENTILATION, mechanical, adjustment formula






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by the Canadian Anesthesiologists' Society.