CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by DEWAN, D. M.
Right arrow Articles by RHYNE, L.
Right arrow Search for Related Content
PubMed
Right arrow Articles by DEWAN, D. M.
Right arrow Articles by RHYNE, L.

Canadian Journal of Anesthesia, Vol 29, 355-358, Copyright © 1982 by Canadian Anesthesiologists' Society

Sodium Citrate Premedication in Elective Caesarean Section Patients

DAVID M. DEWAN 1, W.D. R. WRITER 1, A. SCOTT WHEELER 1, FRANCIS M. JAMES III 1, HERBERT M. FLOYD 1, TERRENCE D. BOGARD 2, and LEONARD RHYNE 3

1 Wake Forest University, Bowman Gray School of Medicine, Forsyth Memorial Hospital, 3333 Silas Creek Parkway, Winston-Salem, North Carolina 27103, U.S.A.
2 Department of Anaesthesia
3 Family Practice and Community Medicine; Wake Forest University, Bowman Gray School of Medicine, Forsyth Memorial Hospital, 3333 Silas Creek Parkway, Winston-Salem, North Carolina 27103, U.S.A.

The pH and volume of gastric contents from thirty-three patients undergoing elective caesarean section with thiopentone, nitrous oxide, succinylcholine anaesthesia were examined. Twenty patients received Gelusil® 30 ml by mouth and thirteen patients received 30 ml of a 0.15 molar solution of sodium citrate. Following tracheal intubation, gastric fluid was sampled through an 18 French Salem sump tube placed orally.

Mean pH following Gelusil® was 4.54 ± 2.45 (SD) and 2.29 ± 1.77 following sodium citrate. This difference was statistically different (P < 0.05). There was no difference in gastric volume between the two groups.

Thirty-five per cent of patients receiving Gelusil® had a pH < 2.5. This low pH was more likely to occur with prolonged intervals between drug administration and sampling. Significantly more patients receiving sodium citrate had a low pH (85 per cent) and this low pH was not related to the duration of interval between administration and sampling.

This study demonstrates that 30 ml of 0.15 molar sodium citrate is not a satisfactory alternative to 30 ml of Gelusil® for increasing gastric pH in the parturient when given sixty minutes before operation.

Note:

Presented in part at the Annual Meeting, Canadian Anaesthetists' Society, Halifax, Nova Scotia, June 1981.

Key Words: PREMEDICATION, antacid, sodium citrate • SURGERY, caesarean section






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1982 by the Canadian Anesthesiologists' Society.