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Canadian Journal of Anesthesia, Vol 29, 377-380, Copyright © 1982 by Canadian Anesthesiologists' Society

Effects of Massive Overdose of Epidural Morphine Sulphate

PAMELA J. MASOUD 1 and CLOID D. GREEN 1

1 Veterans Administration Medical Center, Omaha, Nebraska

A postoperative patient injected with epidural morphine, 60 mg, developed transient left bundle branch block and somnolence. The overdose was effectively treated with a continuous naloxone infusion for 19 hours. Analgesia persisted for an additional 19.5 hours. There was no evidence of sympathetic blockade or narcotic related neurotoxicity.

Key Words: ANALGESIA, epidural morphine • COMPLICATIONS, epidural morphine overdose






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Copyright © 1982 by the Canadian Anesthesiologists' Society.