CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by JULLIEN, Y.
Right arrow Articles by DU CAILAR, J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by JULLIEN, Y.
Right arrow Articles by DU CAILAR, J.

Canadian Journal of Anesthesia, Vol 29, 468-472, Copyright © 1982 by Canadian Anesthesiologists' Society

Perturbation Fonctionnelle Prolongee de la Secretion de Prolactine Apres Chirurgie Sous Neuroleptanalgesie

YVES JULLIEN 1, GÉRARD DESCH 2, ANDRÉE BONARDET 2, DOMINIQUE ALLOUA 1, MARC DERODEZ 1, BERNARD DESCOMPS 2, and JACQUES DU CAILAR 1

1 Département d'Anesthésie-Réanimation A, Centre Hospitalier Universitaire, Hôpital Saint-Eloi
2 Laboratoire de Biochimie C, Centre Hospitalier Universitaire, Hôpital Saint-Charles; 34059 Montpellier Cedex, France

Plasma level of prolactin and its response to the injection of haloperidol were measured in nine women before and after elective gynecological surgery under neuroleptanalgesia using dextromoramidedroperidol combination.

The day before the operation, the injection of haloperidol 0.25 mg intramusculary increases the concentration of PRL by 5.4 ± 1.9 ng/ml, while this response is completely abolished the day following the operation.

Two days later, a tenfold increase in the dose of haloperidol (2.5 mg I.M.) is necessary to obtain a PRL response that equals that observed pre-operatively (5.8 ± 1.2 ng/ml).

The low plasma levels observed 24 and 48 hours post-operatively compared to the pre-operative level, illustrate a prolonged functional disturbance of the secretion of PRL.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1982 by the Canadian Anesthesiologists' Society.