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Canadian Journal of Anesthesia, Vol 29, 539-542, Copyright © 1982 by Canadian Anesthesiologists' Society

Bolus Intravenous Nitroglycerin for St-Segment Depression not Associated with Increased Myocardial Oxygen Demand

ERCUMENT A. KOPMAN M.D.1 and ARTHUR F. DEL REAL M.D.1

1 Department of Anesthesiology, Washington University School of Medicine, 660 South Euclid, St. Louis, Missouri, 63110

Ischaemic ST-segment changes may occur in patients with coronary artery disease when myocardial oxygen consumption is increased as a result of hypertension, tachycardia or increased contractility. Ischaemia can also occur as the result of decreased coronary perfusion pressure caused by hypotension or coronary artery spasm. We report ST-segment depression in the absence of hypertension, tachycardia or hypotension. The response to bolus intravenous nitroglycerin suggested coronary artery spasm as the cause.

Key Words: HEART, ischaemia, coronary artery spasm, nitroglycerin






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Copyright © 1982 by the Canadian Anesthesiologists' Society.