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Canadian Journal of Anesthesia, Vol 29, 550-562, Copyright © 1982 by Canadian Anesthesiologists' Society

Comparison of the Caffeine Skinned Fibre Tension (Csft) Test with the Caffeine-Halothane Contracture (Chc) Test in the Diagnosis of Malignant Hyperthermia

BEVERLEY A. BRITT M.D., F.R.C.P.(C)1, WANDA FRODIS B.Sc.2, ELIZABETH SCOTT M.Sc.2, MARY-JEAN CLEMENTS B.Sc.3, and LASZLO ENDRENYI Ph.D.4

1 Departments of Anaesthesia and Pharmacology, University of Toronto, Toronto, Canada
2 Department of Anaesthesia, University of Toronto, Toronto, Canada
3 Department of Pharmacology, University of Toronto, Toronto, Canada
4 Departments of Preventative Medicine and Biostatistics, and Pharmacology, University of Toronto, Toronto, Canada

For Reprints: Dr. B.A. Britt, Department of Pharmacology, Medical Sciences Building, University of Toronto, Toronto, Ontario, Canada, M5S 1A8.

We have compared and contrasted two diagnostic tests for Malignant Hyperthermia (MH)-the Caffeine-Halothane Contracture Test and the Caffeine Skinned Fibre Tension Test. Both tests show a strongly positive relationship both with the occurrence of MH reactions and with each other. The former test is more rapid and requires less skill. The latter test can be performed on much less muscle and permits storage of the muscle over prolonged periods of time.

Key Words: HYPERTHERMIA, malignant, caffeine-halothane contracture test, caffeine skinned fibre tension test






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Copyright © 1982 by the Canadian Anesthesiologists' Society.