CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MORISON, D. H.
Right arrow Articles by DE GRAFT-JOHNSON, A.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MORISON, D. H.
Right arrow Articles by DE GRAFT-JOHNSON, A.

Canadian Journal of Anesthesia, Vol 29, 622-626, Copyright © 1982 by Canadian Anesthesiologists' Society

Alfathesin and Etomidate for Minor Outpatient Anaesthesia

DAVID H. MORISON M.B., Ch.B., F.R.C.P.(C)1, GEOFFREY L. DUNN M.B., B.S., F.R.C.P.(C)1, and AMA DE GRAFT-JOHNSON M.B., Ch.B.1

1 Section of Anaesthesia, Chedoke-McMaster Hospitals and Department of Anaesthesia, McMaster University, Hamilton, Ontario, L8N 3Z5

Etomidate was compared with alfathesin for induction and maintenance of anaesthesia in a double-blind fashion in 48 fit patients undergoing minor gynaecological operations as outpatients. The patients were randomized to receive either etomidate 0.3 mg·kg-1 or alfathesin 75 µl·kg-1 as intravenous induction agents. All patients received fentanyl 1 µg·kg-1 and breathed 70 per cent nitrous oxide in oxygen. Cardiovascular changes were minimal in both groups and there was less depression of minute volume with etomidate. The incidence of side effects including pain upon injection, involuntary movements, and postoperative nausea and vomiting was higher following etomidate. Recovery was equally rapid in both groups. No adverse reactions were seen. Alfathesin would appear to be preferable to etomidate as an induction and maintenance agent in unpremedicated fit outpatients undergoing minor gynaecological operations.

Key Words: ANAESTHETICS, Intravenous, alfathesin, etomidate • SURGERY, outpatient gynaecology






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1982 by the Canadian Anesthesiologists' Society.