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Canadian Journal of Anesthesia, Vol 30, 419-421, Copyright © 1983 by Canadian Anesthesiologists' Society

Atrial Fibrillation Following Physostigmine

ANTHONY H. MAISTER MB CHB(UCT) FFARCS(E)1

1 Department of Anesthesiology, Harbor/UCLA Medical Center, 1000 W. Carson Street, Torrance, California 90509

The side effects of physostigmine, a tertiary amine anticholinesterase agent commonly used to treat postanaesthetic depression caused by a large number of drugs, are thought to be fairly mild. A case is reported in which atrial fibrillation followed a total dose of 2 mg of this drug to a patient who was slow in recovering from a general anaesthetic. The arrythmia was self-limiting and required no therapy. Indications and precautions for the use of physostigmine are discussed.

Key Words: ANTAGONISTS, MISCELLANEOUS: physostigmine • HEART: arrhythmia, atrial fibrillation






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Copyright © 1983 by the Canadian Anesthesiologists' Society.