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Canadian Journal of Anesthesia, Vol 31, 678-680, Copyright © 1984 by Canadian Anesthesiologists' Society

Clinical Reports: The Reversal of Epidural Morphine Induced Somnolence with Physostigmine

MARK S. SHULMAN MD1, ALAN SANDLER MD FRCP(C)1, and JOHN BREBNER MD FRCP(C)1

1 Toronto General Hospital, Department of Anaesthesia, University of Toronto, Toronto, Ontario

Address correspondence to: Dr. A. Sandier, Department of Anaesthesia, Toronto General Hospital, 101 College Street, Toronto, Ontario, M5G 1L7.

Two case reports are presented of patients with postthoracotomy pain treated with epidural morphine who developed somnolence several hours after the procedure. Physostigmine, 1 mg IV successfully reversed the somnolence without any effect on analgesia.

Key Words: ANAESTHETIC TECHNIQUES: epidural • ANALGESICS: morphine • COMPLICATIONS: somnolence • ANTAGONISTS, MISCELLANEOUS: physostigmine






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Copyright © 1984 by the Canadian Anesthesiologists' Society.